Title:
The Effect of Estrogen and Progesterone Levels on Uterine Contractions in Term and Postterm Pregnancy

Authors:
Ayça K. KÜÇÜKYURT; M.D. Cansel TANRIKULU; M.D. N. Büşra HANOĞLU; M.D, Turkey

Abstract:

Aim and Background: In our study, it is aimed to determine the estrogen and progesterone levels in term and postterm pregnancies, to investigate the effects of these levels on labor and to contribute to the understanding of the mechanism that causes postterm labor, to predict this situation or to pioneer the development of possible strategies to prevent its negative effects.

Material and Methods: Our study consist of pregnant women that they were between 37-41 weeks of age, which correlated with the last menstrual period and the ultrasonography results performed in the first trimester of 100 people who applied to Health Sciences University Istanbul Training and Research Hospital, and the fetal development was found to be compatible with the calculated gestational age in the third trimester examinations. It consists of two main groups, namely the term pregnant (TG) group of 50 people, and the postterm pregnant (PTG) group of 50 people, who were confirmed to have passed the 41st gestational week with the same method. Both groups were divided into two subgroups of 25 each, each with and without pain; A total of 4 study groups were formed as painful TG, painless TG, painful PTG, and painless PTG. The serum progesterone and estrogen levels of the patients were measured and compared statistically before labor.

Results: The comparisons made in our study shows that there are no statistically significant differences observed between the term and postterm pregnant groups, except for the gestational week. The comparisons of pregnant women with pain; Similarly, in the comparison of term and postterm groups in terms of estrogen and progesterone values, it is seen that there is no statistically significant difference in parameters other than gestational week.

Conclusion: As a result of our study, no statistically significant difference was found in terms of estrogen and progesterone levels between term and postterm pregnant women and between those with and without pain. Based on this, we can conclude that estrogen and progesterone levels cannot be used as an indicator of the onset of labor between term and postterm pregnancies.

DOI: http://dx.doi.org/10.51505/ijmshr.2023.7403