Title:
Ovulatory Versus Anovulatory Polycystic Ovary Syndrome Phenotypes: is There Really Any Effect on Laboratory, Clinic and Metabolic Profiles for Turkish Women?

Authors:
Emre Sinan GÜNGÖR; Assoc Prof. Ayça K. KÜÇÜKYURT; M.D. Melek KARA; M.D., Turkey

Abstract:

Aim

Polycystic ovary syndrome (PCOS) is a common disorder and different diagnostic criterias are used for its diagnosis. The purpose of this study is to evaluate any change in insulin metabolism in anovulatory PCOS patients and compare laboratory and clinical parameters between ovulatory and anovulatory PCOS patients diagnosed using Rotterdam criteria

Methods

Hyperandrogenic women with ovulatory cycles and polycystic ovarian morphology (PCOM) and hyperandrogenic women with oligo anovulation and PCOM, respectively, were found in two groups of 132 people with PCOS between the ages of 20 and 40. Blood pressure, waist-to-hip ratio, and Body Mass Index (BMI) were mentioned as demographic factors. Blood samples were taken on days three through five of a menstrual cycle. Initial laboratory testing included measurements of fasting blood sugar and insulin levels, luteinizing hormone (LH), follicle-stimulating hormone (FSH), estradiol (E2), total and free testosterone, prolactine, free T3, free T4, thyroid stimulating hormone (TSH), and lipid profile.

Results

Anovulatory patients were significantly younger than ovulatory patients. Bleeding day in mens were similar between the groups but menstrual cycle length was significantly longer among women with anovultory PCOS (p=0.0001).BMI values, waist/hip ratios and diastolic blood pressures were similar but systolic blood pressures were significantly higher for anovultory patients (p=0.003).LH, total testosteron levels,fT3 and fT4 levels were significantly higher for anovulatory patients. Lipid profiles were similar between the groups but total cholesterol levels were higher among anovulatory group (p=0.02).

Conclusions

DOI: http://dx.doi.org/10.51505/ijmshr.2023.7404