Title:
Macrophage Activation Syndrome: Report of Two Clinical Cases in the Biological Hematology Department of Avicenna Military Hospital, Marrakech

Authors:
Dr J.FARAHAT, Dr A.BOUCHEHBOUN, Pr. H.ELYAHYAOUI, Pr. M.CHAKOUR, Morocco

Abstract:

Macrophage activation syndrome (MAS) is a rare but serious immunological emergency often associated with chronic inflammatory diseases. It represents a secondary form of hemophagocytic lymphohistiocytosis (HLH) and is characterized by uncontrolled immune system activation. We report here two clinical cases identified within a biological hematology laboratory, illustrating the varied presentations, diagnostic challenges, biological features, and multidisciplinary management of MAS.

DOI: http://dx.doi.org/10.51505/ijmshr.2025.9308