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IJMSHR

Title:
Fermented Herbal Preparation Regulated Leukocyte Subsets and Increased the Life Span in Conventional Strain of Rodent

Authors:
Nobuo Yamaguchi, Hirokazu Okamoto, Keiko Kawasaki, and Nurmuhamamt Amat, Japan

Abstract:
Introduction:
Prolonged IRS promised to induced immunological dysfunction with qualitative and quantitative resulted in life-related diseases, yet, only a small part of affected individuals seek medical attention. Several studies have described complementary and alternative medicine (CAM) as effective strategies for improving leukocyte subset through safety root such as TCM, Hot-spring hydrotherapy and fermented food. The purpose of this study was to provoke the effect of a fermented herbal preparation (FHP) to immunological regulation through total life span and fertility function.
Methods:
In this approach of alternative study, participants with prolonged IRS lasting 100 weeks were randomly allocated into two groups: a fermented derivatives group and a control group. The group consumed fermented herbal preparation consisting of 80 sorts of herbs and fruits daily for two years, whereas the control group did not. The primary result was IRS severity as measured FHP by digital scale. Secondary outcomes included sleep quality, dysfunction symptoms, and quality of life as measured FHP, respectively.
Results:
Of 100 individuals screened, 99 completed the study. The mean change the immunological dysfunction in IRS severity was significantly larger in the control group than in the experimental group at 0 day and improvements in IRS severity was recovered at 25, 50, 75 and 100 weeks follow-up. However, FHS antagonist hastened death and FHP ameliorated several age-related diseases with decreased ddY activation in the brain and prolonged survival in ddY mice experimental period.
Conclusion:
The present results suggest that the fermented herbal preparation formulation reduces immunological dysfunction in rodent and improves fertile activity and prolonged life span. FHP ameliorated several age-related diseases with activation in the brain and prolonged survival in ddY mice.

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