When it comes to malignant neoplasms of the liver, their overall division is primary and secondary. Primary ones are those tumors that originate from liver tissue itself, and secondary are tumors that originate from another organ and have metastases present in the liver. Every year there are around 360 people diagnosed with a primary liver tumor, and it is more common in men and more common in the age group of over 65. The method used for the purposes of this thesis is a retrospective analysis of the data obtained from the State Statistical Office of the Republic of Northern Macedonia and outpatient polyclinic morbidities. The paper analyzes the total number of patients in Radovis, Stip and Probistip in 2007 and 2018 and deceased patients at the level of the Republic of Northern Macedonia in 2007 and 2017. In comparison of the number of deaths in 2007 and with those in 2017 it can be concluded that the number of deaths has decreased from 207 to 143 or 64 patients. This is thanks to the development and widespread use of imaging methods such as UC,CT and MRI used to detect the disease in the earlier phase. Mortality has also been reduced due to the modern the rapeuticapproach which provide greater survival.