Title:
Ergotism- a Forgotten Enemy

Authors:
Dr. S. Bharani, Dr. Nithya Priyadarshini, Dr. Renu Devaprasath, Dr. Anand Karthik, India

Abstract:

Background:
Ergot alkaloid medications are used for the treatment of migraine, vascular headache, control of PPH. Ergotism is an uncommon but serious condition caused by intense peripheral vasospasm following ergot alkaloid use. Although its incidence has declined, it may still present in patients using ergotamine-containing medications for migraine. Early recognition is crucial to prevent irreversible ischemic injury. Our case emphasizes the potential for complete reversibility of vascular changes if recognized early. This case highlights the importance of considering ergotism in patients with unexplained ischemia and a history of ergotamine use. Prompt diagnosis, discontinuation of the ergot and other vasoconstrictors, initiation of vasodilator therapy with sodium nitroprusside and timely consideration of endovascular intervention can prevent irreversible ischemia.

DOI: http://dx.doi.org/10.51505/ijmshr.2026.1014